No phaseNot yet recruiting
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation (EPIC-AIR)
- Sponsor
- University of Leicester (Academic or other)
- Enrolment
- 80 planned
- Conditions
- Cardiovascular Disease; Asthma; COPD; Interstitial Lung Disease Due to Systemic Disease; Heart Failure; Coronary Heart Disease (CHD)
- Interventions
- Progressive Walking Exercise Programme; Real-time air quality information and guidance
- Ages
- adults, older adults
- Registry
- NCT07500948
From the registry
The primary objective of EPIC-AIR is to evaluate the feasibility and potential effectiveness of integrating real-time air pollution monitoring into cardiac rehabilitation (CR) and pulmonary rehabilitation (PR) programmes via an online platform that delivers both exercise prescription and air pollution guidance. Specific objectives are: (1) to determine whether access to real-time air quality data reduces modelled ambient pollution exposure (PM2.5, PM10 and NO2) during outdoor physical activity in CR/PR patients and healthy volunteers; (2) to assess the feasibility of the trial design, including recruitment, randomisation, retention, adherence and completeness of outcome data; (3) to measure the impact of the intervention on physical activity levels, health-related quality of life and cardiovascular biomarkers; and (4) to inform the design and sample size of a future definitive randomised controlled trial
Primary outcomes
- Weekly time-weighted mean modelled ambient PM2.5 concentration during moderate-to-vigorous physical activity
- Weekly time-weighted mean modelled ambient PM10 concentration during moderate-to-vigorous physical activity
- Weekly time-weighted mean modelled ambient NO2 concentration during moderate-to-vigorous physical activity