No phaseEnrolling by invitation
Inherited and Environmental Risks Acting on Body Weight (INTERACT)
Genetic and Environmental Contributions to Obesity Pathogenesis
- Sponsor
- University of Washington (Academic or other)
- Enrolment
- 110 planned
- Conditions
- Genetics; Obesity
- Interventions
- Diet modification
- Ages
- adults
- Registry
- NCT07430852
From the registry
The goal of this research is to investigate genetic and environmental factors that contribute to obesity through brain inflammation. The main questions are 1) if identical twins, who differ in food consumption habits, have differences in adiposity markers and brain inflammation and 2) if signs of brain inflammation in response to a specific diet is modified by genetics.
Primary outcomes
- Study 1: Hypothalamic Gliosis
- Study 2: Hypothalamic Gliosis