No phaseRecruiting
A Study of the MIND Diet for Persons With Multiple Sclerosis
Randomized Controlled Trial of MIND Diet for Neuroprotection and Symptom Management in MS
- Sponsor
- Icahn School of Medicine at Mount Sinai (Academic or other)
- Enrolment
- 100 planned
- Conditions
- Multiple Sclerosis
- Interventions
- Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet; Small Group
- Ages
- adults, older adults
- Registry
- NCT06992115
From the registry
This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly assigned to one of two arms: the diet intervention arm or the "continue current diet"/control arm. Participants randomized to the dietary intervention arm will change their diet to follow a MIND dietary pattern for one year; diet-related education and programming is provided to support this change. Participants randomized to the continue/control arm will be asked to continue their current dietary habits, without major change for one year; multiple sclerosis (MS) MS-related related education and programming (unrelated to diet) is provided. All participants will be asked to provide blood \& stool samples and to complete online questionnaires \& three in-person assessments.
Primary outcomes
- Changes in plasma neurofilament light chain (NfL)