TrialPhase 4Active, not recruiting
GLP-1s to Enhance Lasting Optimal Weight (GLOW)
Effects of Tirzepatide on Fat-Free Mass, Bone and Physical Function in Older Adults - a Pilot Study
- Sponsor
- Wake Forest University Health Sciences (Academic or other)
- Enrolment
- 40 enrolled
- Conditions
- Obesity
- Interventions
- Tirzepatide
- Ages
- older adults
- Registry
- NCT06861439
From the registry
The goal of this study is to examine how tirzepatide affects body composition, bone health, and physical performance in older adults over a nine-month period. Participants will take tirzepatide weekly, have clinic visits every 4 weeks, meet study doctor and registered dietitian every 4 weeks in person or video conference, attend group intervention sessions twice a month via video conference, weigh daily with a study-provided smart scale, keep a record of all foods and beverages consumed, and use a study-provided activity tracker to keep track of daily step counts.
Primary outcomes
- Change in total body lean mass
- Change in appendicular lean mass
- Change in total body fat mass
- Change in total hip bone mineral density