No phaseRecruiting
Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity
Interactive Roles of Cardiorespiratory Fitness and Adiposity on Recovery of Impaired Glucose and Vascular Control After Physical Inactivity
- Sponsor
- Miami University (Academic or other)
- Enrolment
- 48 planned
- Conditions
- Metabolic Disorders; Physical Inactivity; Vascular Disease Risk
- Interventions
- reduced physical activity
- Ages
- adults
- Registry
- NCT06842225
Full record on ClinicalTrials.gov
From the registry
The far-reaching negative health effects of the reduced physical activity (RPA) epidemic are often overlooked by the general population and health professionals. Short-term RPA induces cardiometabolic dysfunction, including impaired glucose control and vascular function, that may precede disease development. The impact of existing health status on RPA-induced cardiometabolic dysfunction and recovery of impaired glucose control following RPA is unexplored. Thus, the investigators' objectives are 1) to investigate the effect of existing health status (cardiorespiratory fitness and adiposity) on the recovery of impaired glucose control following a period of RPA and 2) to determine the role of vascular function as a mechanism of impaired glucose control. The investigators' final objective is to 3) expose undergraduate students to meritorious biomedical clinical research methods. The investigators have piloted the clinical research methods and analysis with undergraduate researcher associates and are well-prepared to complete this proposal. Preliminary data show that low…
Primary outcomes
- Changes in Daily Physical Activity
- Oral Glucose Tolerance Test (OGTT)
- Continuous Glucose Monitoring
- Femoral Artery Blood Flow
History
Study completion expected
Primary completion expected
Last registry update
Started
Registered