Early phase 1Not yet recruiting
Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle (DELDEX)
A Randomised, Placebo Controlled Clinical Trial of Dexmedetomidine as Part of a Sleep Promotion Bundle to Improve Sleep in Intensive Care
- Sponsor
- University of Alberta (Academic or other)
- Enrolment
- 50 planned
- Conditions
- Sleep; Delirium; ICU Hospitalization; Critical Illness
- Interventions
- Dexmedetomidine; Control (placebo) group
- Ages
- adults, older adults
- Registry
- NCT06824077
Full record on ClinicalTrials.gov
From the registry
Patients frequently experience problems with sleep while admitted to the ICU. Good sleep is important in ensuring that your immune system responds properly to infection, for your heart to function optimally, and to support normal brain function such as memory. To address sleep problems in the ICU, a bundle of interventions to support more normal sleep are provided. These bundles consist of medications such as sedatives and environmental changes such as less frequent times being assessed overnight and noise reduction strategies. Although medications can make patients appear to be sleeping, most medications do not provide patients with restful sleep. More research is needed on medications that better mimick restful sleep. One such medication is dexmedetomidine. When formally measured dexmedetomidine can make sleep appear more like a patient sleeping at home as compared to the hospital. The purpose of this study is to test whether giving a patient in the intensive care unit dexmedetomidine helps have a more restful sleep and possibly be more alert and/or interactive the next day. To…
Primary outcomes
- Recruitment rate
History
Primary completion expected
Expected to start
Last registry update
Registered