No phaseCompleted
Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
Impact of Cognitive Behavioral Therapy on Neural, Inflammatory, & Autonomic Markers in a Sample With PTSD and Cardiovascular Risk: Protocol for a Pilot Randomized Controlled Trial
- Sponsor
- Massachusetts General Hospital (Academic or other)
- Enrolment
- 6 enrolled
- Conditions
- Posttraumatic Stress Disorder
- Interventions
- Cognitive processing therapy
- Ages
- adults, older adults
- Registry
- NCT06429293
Full record on ClinicalTrials.gov
From the registry
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular disease (CVD) risk. Further, this study will test the hypothesis that CPT reduces CVD risk through its effects on inflammation and autonomic function and that these changes are driven by changes in stress-related neural activity (SNA)
Primary outcomes
- Arterial inflammation
- Heart rate variability
History
Last registry update
Primary completion
Registered
Started