Phase 4Recruiting
Prescription of Letrozole for Uterine Myoma (PLUM)
Letrozole for Treatment of Uterine Fibroids: A Randomized, Placebo-Controlled Trial
- Sponsor
- University of California, San Francisco (Academic or other)
- Enrolment
- 140 planned
- Conditions
- Leiomyoma, Uterine; Leiomyoma; Fibroid; Fibroid Uterus
- Interventions
- Letrozole 2.5mg; Placebo
- Ages
- adults
- Registry
- NCT06143631
From the registry
The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and quality of life as well as leiomyoma and uterine size.
Primary outcomes
- Uterine leiomyoma-related symptom severity over 12 weeks of treatment