No phaseRecruiting
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps (COOP)
Colonoscopy Versus Stool-based Testing for Older Adults With a History of Colon Polyps
- Sponsor
- Dartmouth-Hitchcock Medical Center (Academic or other)
- Enrolment
- 6,434 planned
- Conditions
- Colorectal Polyp; Colorectal Neoplasms; Colorectal Adenoma; Colorectal Cancer; Digestive System Disease
- Interventions
- FIT; Colonoscopy
- Ages
- older adults
- Registry
- NCT05612347
From the registry
This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of colorectal polyps who are due for surveillance colonoscopy.
Primary outcomes
- Incidence of advanced neoplasia in each study group, annual FIT and colonoscopy, assessed by comparing the detection of advanced neoplasia between the two study groups.