No phaseRecruitingAge-related condition

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

Sponsor
Kuopio University Hospital (Academic or other)
Enrolment
200 planned
Conditions
Alzheimer Disease; Frontotemporal Dementia; Dementia With Lewy Bodies
Interventions
Gamma tACS (40 Hz) over the superior parietal cortex
Ages
adults, older adults
Registry
NCT05326750

Full record on ClinicalTrials.gov

From the registry

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Primary outcomes

  • Changes in Rey Auditory Verbal Learning Test score
  • Changes in Rey Auditory Verbal Learning Test, recognition
  • Changes in orientation to time and place (MMSE questions 1-10)
  • Changes in Trail Making A & B tests

History

  1. Primary completion expected

  2. Last registry update

  3. Started

  4. Registered