No phaseCompleted

Genetic and Cognitive Predictors of Aphasia Treatment Response

Laying the Groundwork for Personalized Medicine in Aphasia Therapy: Genetic and Cognitive Predictors of Restorative Treatment Response

Sponsor
Ohio State University (Academic or other)
Enrolment
35 enrolled
Conditions
Aphasia
Interventions
Cued picture-naming therapy
Ages
adults, older adults
Registry
NCT05179538

Full record on ClinicalTrials.gov

From the registry

Aphasia, or language impairment after a stroke, affects approximately 2 million people in the United States, with an estimated 180,000 new cases each year. The medical community cannot predict how well someone with aphasia will respond to treatment, as some people with aphasia are poor responders to intervention even when participating in empirically supported treatments. There is a strong likelihood that genetics play a role in language recovery after stroke, but very little research has been dedicated to investigating this link. This study will investigate whether two genes and cognitive abilities, such as memory, predict responsiveness to aphasia therapy for word-retrieval difficulties.

Primary outcomes

  • Percent of pictures named correctly
  • Percentage of pictures named correctly

History

  1. Last registry update

  2. Primary completion

  3. Registered

  4. Started