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Phase 3Active, not recruitingAge-related condition

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)

Sponsor
University of Florida (Academic or other)
Enrolment
1,683 planned
Conditions
Intracranial Arteriosclerosis; Stroke
Interventions
Ticagrelor + Aspirin; Rivaroxaban + Aspirin; Clopidogrel + Aspirin; Risk Factor Management
Ages
adults, older adults
Registry
NCT05047172

Full record on ClinicalTrials.gov

From the registry

The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.

Primary outcomes

  • Number of participants with parenchymal ICH or non-ICH major hemorrhage
  • Number of participants with ischemic stroke, intracerebral hemorrhage or vascular death

History

  1. Primary completion expected

  2. Last registry update

  3. Started

  4. Registered