Early phase 1Recruiting
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
MC210501 Differences in Immunological Effects of Vitamin D Replacement Among Black/ African American (AA) Prostate Cancer Patients With Localized Versus Metastatic Disease
- Sponsor
- Mayo Clinic (Academic or other)
- Enrolment
- 220 planned
- Conditions
- Localized Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Locally Recurrent Prostate Carcinoma; Metastatic Prostate Carcinoma
- Interventions
- Cholecalciferol; Quality-of-Life Assessment; Biospecimen Collection
- Ages
- adults, older adults
- Registry
- NCT05045066
Full record on ClinicalTrials.gov
From the registry
This early phase I is to find out how common vitamin D insufficiency is among African American patients with a history of prostate cancer that has not spread to other parts of the body (localized) or has spread to other places in the body (metastatic) and how vitamin D insufficiency affects the immune system. This study also aims to find out if replacing vitamin D results in normalization of the immune function. Information from this study may benefit prostate cancer patients by identifying vitamin D insufficiency which in several studies had been found to contribute to more aggressive prostate cancers.
Primary outcomes
- Change in circulating immunological cell function
History
Study completion expected
Primary completion expected
Last registry update
Started
Registered