No phaseCompleted
Blood Flow Restriction Exercise in Patients With Pancreatic, Biliary Tract, and Liver Cancer (PREV-Ex)
Blood Flow Restriction Exercise in the Perioperative Setting to Prevent the Loss of Muscle Mass in Patients With Pancreatic, Biliary Tract, and Liver Cancer - the PREV-Ex Randomized Controlled Trial
- Sponsor
- Karolinska Institutet (Academic or other)
- Enrolment
- 52 enrolled
- Conditions
- Pancreatic Cancer; Biliary Tract Cancer; Liver Cancer
- Interventions
- Physical exercise
- Ages
- adults, older adults
- Registry
- NCT05044065
Full record on ClinicalTrials.gov
From the registry
In patients with cancer, resistance training appears to be a safe and effective exercise modality to increase both lean muscle mass and strength, as well as attenuates cancer-related fatigue. It may serve as a feasible intervention in these patients to mitigate cachexia, especially if implemented before the onset of cancer cachexia or in a pre-cachectic state. This study is a multicenter randomized controlled trial that will compare a blood flow restricted resistance training intervention during the pre- (prehabilitation) and post-operative (rehabilitation) phase in patients with pancreatic, biliary tract and liver cancer, versus usual care on skeletal muscle and other health-related outcomes.
Primary outcomes
- Skeletal muscle thickness
- Skeletal muscle cross sectional area
History
Last registry update
Study completion
Primary completion
Started
Registered