No phaseCompleted
Low GI Diet Effects on Non-Alcoholic Fatty Liver Disease (LGI-NAFLD)
Effects of an Iso-energetic Low Glycemic Index (GI) Diet on Liver Fat Accumulation and Gut Microbiota Composition in Patients With Non- Alcoholic Fatty Liver Disease (NAFLD)
- Sponsor
- University of Nottingham (Academic or other)
- Enrolment
- 12 enrolled
- Conditions
- Fatty Liver; Nutritional and Metabolic Disease
- Interventions
- low glycemic index diet; High glycemic index diet
- Ages
- adults, older adults
- Registry
- NCT04415632
From the registry
A 2 x 2 cross-over dietary intervention trial designed to investigate the effects of low glycemic index (LGI) versus high glycemic index (HGI) diet on hepatic fat accumulation and gut microbiota composition in participants with NAFLD. Participants will be allocated randomly to a 2-week either high GI (HGI) or low GI (LGI) diet followed by a 4-week wash-out period and then the LGI or HGI diet, opposite to the first 2-weeks (N= 16).
Primary outcomes
- Change in Liver Fat Content From Baseline to End of Each 2-Week Dietary Intervention