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Stool DNA to Improve Colorectal Cancer Screening Among Alaska Native People

Randomized Controlled Trial of the Stool DNA Test to Improve Colorectal Cancer Screening Among Alaska Native People

Sponsor
Alaska Native Tribal Health Consortium (Academic or other)
Enrolment
2,029 enrolled
Conditions
Colorectal Cancer
Interventions
Multi-target stool DNA test; Colonoscopy
Ages
adults, older adults
Registry
NCT04336397

Full record on ClinicalTrials.gov

From the registry

Only 59% of Alaska Native people have been adequately screened for colorectal cancer (CRC) despite having the highest reported incidence of CRC in the world. A new at-home multi-target stool DNA screening test (MT-sDNA; Cologuard®) with high sensitivity for pre-cancerous polyps and CRC is now available. MT-sDNA has not been tested for feasibility or acceptability within the Alaska tribal health care delivery system, and it is unknown whether use of this new test will increase Alaska Native CRC screening rates. The long-term study goal is to improve screening and reduce CRC-attributable mortality. The objective of this application is to test the effectiveness of MT-sDNA for increasing CRC screening in Alaska Native communities using a mixed methods, community-based participatory research (CBPR) approach. The study will be conducted in collaboration with regional Tribal health organizations responsible for providing health care to geographically remote Alaska Native communities. Although the proposed implementation strategy is evidence-informed and promising, it is novel in that…

Primary outcomes

  • Colorectal Cancer Screening by Study Arm

History

  1. Last registry update

  2. Results first posted

  3. Primary completion

  4. Started

  5. Registered

Papers citing this trial