Phase 1/2Active, not recruitingAge-related condition
Tocotrienols for Obesity of Postmenopausal Women (VitE-obesity)
Actions of Dietary Tocotrienols on Obesity
- Sponsor
- Texas Tech University Health Sciences Center (Academic or other)
- Enrolment
- 60 enrolled
- Conditions
- Obesity; Postmenopausal Women
- Interventions
- placebo softgel; DeltaGold® Tocotrienol 70%
- Ages
- children, adults, older adults
- Registry
- NCT03705845
Full record on ClinicalTrials.gov
From the registry
Postmenopausal women are at a risk of excessive weight gain, bone loss, hypertension, and metabolic syndrome. Obesity-induced chronic low-grade inflammation is initiated by excess nutrients in metabolic cells. Recent studies have indicated tocotrienols (one kind of vitamin E, a potent antioxidant) supplement may be good for mitigating negative impacts of obesity in postmenopausal women. The purpose of the study is to examine the effect of 24-week tocotrienols on obesity-associated outcome measurements in postmenopausal women. The investigators will enroll 60 qualified women at the start of the study and randomly assigned to no tocotrienols (placebo) or tocotrienols group for 24 weeks. Obesity-associated measurements will be recorded using blood, urine, adipose tissue, and fecal samples. All data will be analyzed statistically.
Primary outcomes
- Fat mass
- visceral adipose tissue
History
Study completion expected
Last registry update
Primary completion
Started
Registered