Phase 4Completed

Diet, Obesity and Genes (DiOGenes) (DIOGENES)

Sponsor: University of Copenhagen (Academic or other)
Enrolment: 1,020 planned
Conditions: Obesity; Metabolic Syndrome; Type 2 Diabetes; Cardiovascular Disease
Interventions: High or low Glycemic Index and high or low Protein Diet
Ages: children, adults, older adults
Registry: NCT00390637

From the registry

Study Title: Diogenes, A randomised controlled trial comparing the effect of reduced-fat diets varying in glycaemic index (high vs. low) and protein content (high vs. normal) on bodyweight in overweight and obese subjects after an initial weight loss.

Primary outcomes

For adults: body weight loss maintenance

Full record on ClinicalTrials.gov

Papers citing this trial

Integrated adipose tissue transcriptomic and miRNA remodeling identifies molecular pathways associated with residual cardiovascular risk after weight loss
Cardiovascular diabetology