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Investigation of cognitive performance and neurometabolic changes using 31P-MRS and 1H-MRS in women during menstruation while on a creatine diet

Investigation of cognitive performance and neurometabolic changes using 31P-MRS and 1H-MRS in women during menstruation while on a creatine diet - Menst

Sponsor
Forschungszentrum Jülich
Enrolment
52 planned
Conditions
Investigation of the influence of the menstrual cycle on brain metabolism, cognitive performance, and blood levels of estrogen and creatine in women.
Interventions
Two-week daily oral supplementation of 15 g/day, followed by a two-week maintenance phase of 8 g/day of the dietary supplement creatine monohydrate following a baseline measurement
Ages
adults
Registry
DRKS00041152

Full record on the German Clinical Trials RegisterSource: WHO ICTRP, processed 14 September 2026

Primary outcomes

  • Investigation of the time course of cerebral metabolic parameters (PCr, ATP, Pi, Cr), cognitive performance, and estrogen and creatine levels in women before and during menstruation. Measurements are performed using 31P-MRS and 1H-MRS, cognitive tests, and blood sampling.

History

  1. Started

  2. Last registry update

  3. Registered