Early phase 1Recruiting
Mechanistic study of orlistat in ameliorating overweight/obesity through modulation of gut microbiota
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
- Enrolment
- 69 planned
- Conditions
- Overweight and Obesity
- Interventions
- Orlistat 120 mg administered three times daily for 12 weeks, combined with a low-calorie diet (1200-1500 kcal/day) and at least 150 minutes of physical activity per week throughout the study period
- Ages
- adults, older adults
- Registry
- ChiCTR2600129223
Full record on the Chinese Clinical Trial RegistrySource: WHO ICTRP, processed 3 August 2026
Primary outcomes
- Percentage change in body weight after 12 weeks of orlistat intervention;
History
Last registry update
Registered
Started