Phase 2/3Status unknown

Weight loss medications on exercise capacity in Pulmonary Arterial Hypertension (PAH) patients

Glucagon-like peptide (GLP-1) Agonist for Patients with Overweight or Obesity and Pulmonary Arterial Hypertension (GO-PAH): An Open-Label Multicentre Proof-of-Concept Study

Sponsor
Sydney Local Health District
Enrolment
20 planned
Conditions
Pulmonary arterial hypertension; Obese; Overweight; Pulmonary arterial hypertension Obese Overweight; Metabolic and Endocrine - Other metabolic disorders; Respiratory - Other respiratory disorders / diseases; Diet and Nutrition - Obesity
Interventions
Semaglutide Dose
Ages
adults, older adults
Registry
ACTRN12626001139369

Full record on ANZCTRSource: WHO ICTRP, processed 21 September 2026

Primary outcomes

  • 6 minute walk distance [6MWT baseline, 26 weeks post treatment, 52 weeks post treatment (primary time point) ]

History

  1. Started

  2. Last registry update

  3. Registered