Papers by Yun Chen · AgingResearch.News

Frontiers in Endocrinology8 Oct
Outcome-specific value of longitudinal clinical information and model complexity for dynamic prediction of type 2 diabetes-related outcomes: a pooled landmarking study
Study in peopleBiomarkers
Paper
Endocrine6 Oct
Cardiovascular safety in middle-aged and older men under testosterone replacement therapy: a systematic review and meta-analysis
Meta-analysis of randomised trialsTestosterone
Paper
FASEB Journal30 Sep
4-Octyl itaconate restores parotid gland function in aging mice
The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.
Experiments in miceInterventions
Paper
Ultrasound in Obstetrics & Gynecology28 Sep
Postpartum anthropometric and cardiovascular profile following hypertensive disorders of pregnancy: 12-month follow-up
Cohort study of 201 peopleHypertensive disorders of pregnancy
Paper

Inflammation Research28 Sep
Loss of PP4 drives airway senescence through endoplasmic reticulum stress
Inhibiting the PERK pathway lowered cellular senescence and inflammatory markers in mouse models and cultured human airway cells.Inhibiting the PERK pathway lowered cellular senescence and inflammatory markers in mouse models and cultured human airway cells.
Experiments in human cellsER unfolded protein response
Paper
Frontiers in Cardiovascular Medicine15 Sep
Association of self-reported anxiety and depressive symptoms with incident hypertension among young adults
Cohort study of 2,448 peopleAnxiety disorders
Paper
Lancet3 Sep
Porcine kidney xenotransplantation as a bridge to allotransplantation: a first-in-human study
Trial in peopleKidney
Paper
Neurodegenerative Disease Management26 Aug
Donanemab for early symptomatic AD in the UK-indicated population: safety and efficacy in those who are non-carriers or heterozygous for APOE ε4
Trial in peopleInterventions
Paper
Diabetes, Obesity & Metabolism24 Aug
Ten-Year Cost-Effectiveness of the Risk Assessment and Management Programme-Diabetes Mellitus (RAMP-DM) Relative to Usual Care in Hong Kong Public Primary Care: A Population-Based Cohort Study
Study in peopleInterventions
Paper
Cell14 Aug
Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human
Experiments in animalsMechanisms
Paper
Archives of Gerontology and Geriatrics13 Aug
Telomerase RNA component knockout is associated with iron accumulation and altered transferrin receptor 1 and ferroportin 1 expression in the liver and lung
Experiments in miceTelomerase and telomere maintenance
Paper
AAIC 2025 Abstract23 Dec
Associations between Alzheimer's disease polygenic risk and postoperative delirium: a prospective cohort study
Study in peoplePopulations
Paper
GSA 2024 Abstract1 Jan
FAMILY HISTORY OF ALZHEIMER’S DISEASE AND LOCUS COERULEUS ACTIVATION IN HEALTHY OLDER AND YOUNGER ADULTS
Study in peopleMechanisms
Paper