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Papers by Pradeep Natarajan

29 results

  1. Nature Communications

    Blood stem-cell mutations linked to serious bacterial infections

    In an analysis of 889,215 people, clonal blood mutations were associated with serious bacterial infections, with a hazard ratio of 1.22.In an analysis of 889,215 people, clonal blood mutations were associated with serious bacterial infections, with a hazard ratio of 1.22.

    Cohort study of 889,215 peopleMechanisms
    Paper
  3. medRxiv

    ASXL1-mutant clonal hematopoiesis links to aortic valve disease

    In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or IL-6 inhibition.In cohort data and cell models, ASXL1 mutations tracked with incident aortic stenosis and promoted valvular calcification that was reduced by IL-1 or IL-6 inhibition.

    Preprint: cohort study of 449,109 peopleASXL1
    Paper