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Papers by Carlos Cruchaga

39 results

  2. Neurology Genetics

    GLP-1 receptor agonists link to lower stroke and Alzheimer risk

    A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.

    Mendelian randomisation in peopleGLP-1 receptor agonists
    Paper
  3. Nature Genetics

    Germline HRD limits therapy-driven clonal hematopoiesis

    Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.

    Cohort study in peopleBlood and immune system
    Paper