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David Spiegel

Works at

  • Yale University

    Professor of Chemistry and of Pharmacology28 Sept 2026medicine.yale.edu

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    News

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    Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

    ResearchNature Aging and 1 more

    Einstein researchers link chaperone-mediated autophagy decline to senescent cell accumulation

    ResearchPR Newswire and 1 more

    Lipid chain elongation marks aging and shortening chains extends worm lifespan

    ResearchNature Aging

    Trials

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    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered1 Oct 2026

    Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes

    Institut de Recherches Cliniques de Montreal

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    Evidence →
    1. Intervention · 66 papersExercise
    2. Gene · 27 papersAPOE
    3. Disease · 128 papersType 2 diabetes
    4. Process · 124 papersInflammation
    5. Biomarker · 42 papersBody mass index
    6. Intervention · 42 papersSmoking

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    • Mechanisms293
    • Interventions409
    • Biomarkers367
    • Populations540
    • AI & data135
    • Industry & policy27
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    • © 2026 AgingResearch.News