Research Square

The impact of acetaminophen on reducing the incidence of postoperative delirium in elderly patients with sepsis in the ICU: A retrospective study and Mendelian randomization analysis

Preprint: study in peopleInterventions

Abstract

Background Sepsis is one of the most common conditions in the intensive care unit (ICU), particularly among elderly patients, with its high incidence and mortality severely affecting patients' quality of life. Delirium is particularly prevalent in sepsis patients, significantly impacting recovery and long-term cognitive function.

The paper

Third Affiliated Hospital of Harbin Medical University

Research Square, 3 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10001390/v1