Health worsened as US adults in a study reached midlife

An observational study compared six groups of Americans born in different periods; one group’s health worsened into midlife, while health behaviours improved.

The Journals of Gerontology, Series B

An observational study analysed health data on people in six US birth cohorts, or groups born in different periods, observed from adolescence to middle age. Researchers used two national studies and compared people with and without a four-year college degree.

In the National Longitudinal Study of Adolescent to Adult Health, general health, mental health and chronic disease worsened as participants reached midlife. Health behaviours improved. Compared with groups in the National Health and Nutrition Examination Survey, participants had worse health than older groups. They generally had worse health than people born in the same period, with some exceptions. Comparisons with younger groups were mixed. Health gaps by education stayed relatively stable with age, with some evidence of widening. These gaps generally widened across birth groups.

Why it matters

The authors concluded that this midlife group will enter old age in worse health than its predecessors.

Caveats

This observational comparison cannot establish why health differed or whether education caused the health gaps. The findings concern US birth cohorts.

The paper

Midlife in crisis? Life course pathways to health at midlife across U.S. cohorts

Lauren Gaydosh, Iliya Gutin, Kathleen Mullan Harris

University of North Carolina at Chapel Hill

The Journals of Gerontology, Series B · 1 Oct 2026

doi.org/10.1093/geronb/gbag138PubMed 42837509