InterventionsAnimals
Spatial modulation of RAF by RAF/MEK glue enables full-dose combination with pan-RAF inhibitor and potent RAS-mutant tumor-selective MAPK and growth inhibition
Cancer Discovery
The paper
Ana Orive-Ramos, Bijaya Gaire, Christos Adamopoulos, Poulikos I. Poulikakos
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Beau Baars, Mathieu Desaunay, Ziyue Kou, Evangelia Matenoglou, Sílvia Coma, Nayeli Gutiérrez, Kevin Mohammed, Stuart A. Aaronson, Jian Jun Jin, Tiphaine C. Martin, Ernesto Guccione, Evripidis Gavathiotis, Jonathan A. Pachter,Icahn School of Medicine at Mount Sinai
Cancer Discovery · 29 Sep 2026