Boronate ester-crosslinked GelMA composite bioink for 3D bioprinting of cell-laden corneal stroma and in vivo evaluation in rabbits

Abstract

Corneal transplantation restores vision by replacing damaged corneal tissue with a donor graft, but the limited supply and variable quality of donor corneas remain major challenges. We therefore developed an engineered corneal substitute using gelatin methacryloyl (GelMA), a modified gelatin.