Assessment of a Pre-Statistical Frailty Harmonization in Five US-Based Studies of Older Adults

Abstract

Pre-statistical harmonization—careful comparison of study-to-study inclusion criteria, protocols, instruments, and data formats—is an essential step in consistently characterizing the Frailty Phenotype across studies. We explored a pre-statistical harmonization strategy for characterizing frailty in ACHIEVE, ARIC, BLSA, NHATS, and STURDY.