Sleep Quality as a Modifier of Plasma pTau217 and GFAP Associations with Cognitive Function

Abstract

Background: Plasma biomarkers, such as neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), phosphorylated tau (pTau217), and total tau (tTau), are associated with cognitive decline. However, the role of sleep quality in modifying these associations remains unclear.