AAIC 2025 Abstract
Connector Hubs Accelerate the Spread of Tau Pathology in Alzheimer's Disease
By Fabian Hirsch, Lukas K. Frontzkowski, Sebastian Niclas Roemer, Show 10 more authorsNicolai Franzmeier
Study in peopleMechanisms
Abstract
Background: Tau accumulation drives neurodegeneration and cognitive decline in Alzheimer’s Disease (AD) and preclinical research suggests that tau spreads transsynaptically across connected neurons.
