BiomarkersHumans2,630 participants10 yearsCohort study

Accelerated Phenotypical Aging in Midlife is Associated with Long‐Term Cognitive Decline in Middle‐Aged Adults

AAIC 2025 Abstract

Abstract

Background: PhenoAge is a multi‐system blood‐based aging marker that uses common clinical tests of glucose metabolism, inflammation and kidney and liver function. This easily‐obtained marker determines whether a person is younger or older on a biological and physiological level than expected by their chronological age.

The paper

Merten N, Baumann MR, Paulsen AJ et al.

AAIC 2025 Abstract · 7 Jan 2026 · CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70856_106183