Differential performance of plasma p ‐tau217 in detecting intermediate vs high Alzheimer's disease neuropathologic change

AAIC 2025 Abstract

Abstract

Background: In vivo detection of intermediate and high Alzheimer's disease neuropathologic changes (ADNC) is key for disease staging and clinical trial enrolment. While a visually positive tau‐PET scan with the FDA/EMA‐approved tracer [ ¹⁸ F]flortaucipir can be considered a reliable proxy of high ADNC (Fleisher et al.

The paper

Karagianni S, Rial AM, van Essen M et al.

AAIC 2025 Abstract · 26 Dec 2025 · CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70856_104257