AAIC 2025 Abstract

Neuroinflammation is a Key Player in the Cognitive Fate of Individuals Who Harbor Alzheimer Disease Neuropathologic Changes

Study in peopleMechanisms

Abstract

Background: Some individuals show no cognitive decline during life despite presence in their brains of Alzheimer disease neuropathologic changes (ADNC) (e.g. amyloid plaques and tangles). Understanding the molecular mechanisms underlying resilience to ADNC could help develop new biomarkers and identify novel therapeutic targets.

The paper