AAIC 2025 Abstract
Prediabetic amylin hypersecretion impairs brain glucose regulation
By Ravichandra Shivalingappa Davargaon, Deepak Kotiya, Noah S. Leibold, Show 3 more authorsFlorin Despa
Experiments in animalsMechanisms
Abstract
Background: Type‐2 diabetes‐related hyperglycemia increases the risk for cognitive decline. Amylin is a centrally‐linked pancreatic hormone that induces satiation. The beneficial metabolic effects of amylin led to regulatory approval of the amylin analog drug, pramlintide, for weight loss.
