AAIC 2025 Abstract
The Ketogenic Diet Restores Brain Metabolism and Gut Microbiome Composition in Female APOE4 Transgenic Mice: A Multiomics Approach
Experiments in animalsInterventions
Abstract
Background: The apolipoprotein ε4 (APOE4) polymorphism is the primary genetic risk factor for Alzheimer's disease (AD). APOE4 carriers exhibit early deficits in brain metabolism and gut microbiome diversity, both elevating AD risk.
