Mammalian cells

Papers on Mammalian cells

14 papers2 new in 30 days

Friday, November 13

bioRxivNov 13

Engineered tool improves DNA editing in mammalian cells

Editing efficiency rose from 4.29% with the original tool to 48.94% with the engineered version in experiments with mammalian cells.Editing efficiency rose from 4.29% with the original tool to 48.94% with the engineered version in experiments with mammalian cells.

A large dark blue-green cell contains a joined protein and cut DNA strands, surrounded by smaller cells with mostly intact strands.

Preprint: animal cell studyInterventions

Tuesday, November 10

Research SquareNov 10

Compact gene editor enables efficient DNA editing in mice

Viral delivery of the editor in mice reduced a cholesterol-regulating protein by about 82% and LDL cholesterol by about 47%.Viral delivery of the editor in mice reduced a cholesterol-regulating protein by about 82% and LDL cholesterol by about 47%.

Mouse livers beside a laboratory mouse, with sparse protein and cholesterol particles around the dark blue-green liver and dense particles around the gray…

Preprint: mouse studyInterventions

Thursday, February 19

Nature CommunicationsFeb 19

Engineered Un1Cas12f1 for multiplex genome editing with enhanced activity and targeting scope

Experiments in miceInterventions

Wednesday, June 11

bioRxivJun 11

TrAEL-seq captures DNA replication dynamics in mammalian cells

Preprint: experiments in cellsAI & data

Thursday, June 27

AntioxidantsJun 27

β-Cyclocitral from Lavandula angustifolia Mill. Exerts Anti-Aging Effects on Yeasts and Mammalian Cells via Telomere Protection, Antioxidative Stress, and Autophagy Activation

Experiments in yeastInterventions

Sunday, April 21

Advances in NutritionApr 21

Effects of (Poly)phenols on Circadian Clock Gene-Mediated Metabolic Homeostasis in Cultured Mammalian Cells: A Scoping Review

Systematic review of animal and cell studiesInterventions

Thursday, September 7

Ageing Research ReviewsSep 7

Effects of nanomaterial exposure on telomere dysfunction, hallmarks of mammalian and zebrafish cell senescence, and zebrafish mortality

Meta-analysis of animal and cell studiesTelomerase and telomere maintenance

Tuesday, November 1

Frontiers in Cell and Developmental BiologyNov 1

The uniformity and stability of cellular mass density in mammalian cell culture

Experiments in cellsMechanisms

Tuesday, March 8

bioRxivMar 8

Decreased spliceosome fidelity inhibits mTOR signalling and promotes longevity via an intron retention event

Preprint: experiments in wormsmTOR signaling

Saturday, October 30

iScienceOct 30

Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity

Experiments in cellsmTOR signaling

Thursday, December 17

VirusesDec 17

Resveratrol, Rapamycin and Metformin as Modulators of Antiviral Pathways

ReviewResveratrol

Tuesday, October 11

Nature CommunicationsOct 11

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Experiments in cellsNicotinamide

Thursday, May 23

NatureMay 23

Mitonuclear protein imbalance as a conserved longevity mechanism

Experiments in wormsMechanisms

Monday, July 17

The Journal of Biological ChemistryJul 17

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

Experiments in cellsmTOR signaling