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University of Cagliari

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Trials

NCT06872151
Phase 4Completed2025114 people12 Mar 2025clinicaltrials.gov
NCT02393482
Phase 4Status unknown202150 people19 Mar 2015clinicaltrials.gov

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Direct AMPK activation modestly lengthens lifespan in short-lived species

ResearchFight Aging!

Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

ResearchNature Aging and 1 more

Senescence-inhibiting isoform Δ133p53α slows premature aging in mice

Researchnpj Aging

Trials

Registered6 Oct 2026

AKG and Brain Health in Aging

Phase 2 · University of Oklahoma

Registered2 Oct 2026

Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

Registered7 Oct 2026

AI-Based Conversational Social Support for Older Adults With Heart Failure

Chang Gung University of Science and Technology

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Intervention · 64 papersExercise
Gene · 22 papersAPOE
Disease · 122 papersCardiovascular disease
Process · 117 papersInflammation
Biomarker · 43 papersBody mass index
Intervention · 42 papersGLP-1 receptor agonists

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Mechanisms293
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Populations561
AI & data141
Industry & policy28

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