Unity Biotechnology
CompanyUnited StatesFounded 2009
Unity Biotechnology develops 2 assets, the furthest in phase 2 (UBX0101 in knee osteoarthritis). Mostly small molecule acting on cellular senescence, apoptosis and MDM2; based in the United States, founded in 2009.
- 2
- Assets
- Furthest stage
- Phase 2
- Raised
- US$206.3m
- 1
- Trial
- 1
- Signal
Pipeline
2Senolytic MDM2/p53 interaction inhibitor that induces apoptosis in senescent cells
Phase 2, Small molecule, Apoptosis, MDM2, knee osteoarthritis
Senolytic BCL-xL inhibitor given into the eye to clear senescent cells from diseased retinal vessels
Discontinued, Small molecule, Cellular senescence, BCL2L1
Full company profiles: pipeline, trials, funding and people.
In the full profile
- Evidence behind the mechanisms6
- Trials1
- Funding rounds and grants2
- Signals3
- Similar companies6
Papers
Safety and Efficacy of Senolytic UBX1325 in Diabetic Macular Edema
NEJM evidence, Apr 22, 2025