Netherlands Heart Institute

• NCT07234422

  Phase 3, Recruiting, 1,100 people, Nov 18, 2025

• Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune-Shielded Heart Valves

  Sep 21, 2026

• The NLRP3-inflammasome inhibitor MCC950 improves cardiac function in a HFpEF mouse model

  Nov 30, 2024

• Deletion of DWORF does not affect cardiac function in aging and in PLN-R14del cardiomyopathy

  Feb 9, 2024

• Insulin-like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence

  2020B005, 2018-30, 2017-11, 2017-21, Sep 11, 2022

• Nicotinamide Riboside Improves Cardiac Function and Prolongs Survival After Disruption of the Cardiomyocyte Clock

  May 9, 2022

• Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis

  Nov 1, 2021

• Age- and sex-related features of atherosclerosis from coronary computed tomography angiography in patients prior to acute coronary syndrome: results from the ICONIC study

  Jan 1, 2021

• Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

  200T401, Aug 14, 2020

• Telomere length and incident atrial fibrillation - data of the PREVEND cohort

  Feb 3, 2017

• Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality

  Oct 31, 2016

Sources: openalex.org, api.crossref.org

• Optimizing Screening Intervals for At-Risk Relatives of Dilated Cardiomyopathy Carrying a TTNtv

  Circulation. Heart failure, Sep 21, 2026

• Early-stage myocardial changes are not aggravated by Western diet or ageing in Mybpc3 c.2373insG heterozygous mice

  The Journal of physiology, Sep 9, 2026

• Sex-specific associations of the plasma-proteome with incident coronary artery disease

  Cardiovascular research, Sep 3, 2026

• Semaglutide and Exercise Synergy in Obesity: Preserving Muscle Mass and Uncovering Organ Crosstalk

  Diabetes & metabolism journal, Jul 15, 2026

• Natural history of thyroid function in ageing: an individual participant data analysis of 137 488 participants from 31 prospective cohort studies

  The lancet. Diabetes & endocrinology, May 1, 2026

• Obicetrapib and ezetimibe enhance LDL receptor-mediated VLDL clearance and regress atherosclerosis on atorvastatin background

  Journal of lipid research, Mar 27, 2026

• Photoporation enables non-viral delivery of prime editing RNP complexes into human iPSC-derived cardiomyocytes for cardiac genome correction

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Mar 21, 2026

• Supplement prevented mitochondrial problems in diseased mice

  Human molecular genetics, Jan 1, 2026

• Reversion of aortic valve cells calcification by activation of Notch signalling via histone acetylation induction

  Signal transduction and targeted therapy, Sep 18, 2025

• Pravastatin reduces all-cause mortality in elderly individuals at risk of liver fibrosis: Post hoc analysis of the PROSPER trial

  JHEP reports : innovation in hepatology, Apr 11, 2025

• Increased 1H-NMR metabolomics-based health score associates with declined cognitive performance and functional independence in older adults at risk of cardiovascular disease

  GeroScience, Oct 22, 2024

• The potential benefit of statin prescription based on prediction of treatment responsiveness in older individuals: an application to the PROSPER randomized controlled trial

  European journal of preventive cardiology, Dec 12, 2023

• Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study

  Circulation. Heart failure, May 16, 2023

• Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study

  GeroScience, May 14, 2023

• Cardiac Troponin, Cognitive Function, and Dementia: A Systematic Review

  Aging and disease, Apr 4, 2023

• Weight loss, visit-to-visit body weight variability and cognitive function in older individuals

  Age and ageing, Jan 11, 2023

• Metabolomic profiles predict individual multidisease outcomes

  Nature medicine, Sep 23, 2022

• Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization

  The Journal of clinical endocrinology and metabolism, Mar 21, 2022

• Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study

  BMC geriatrics, Mar 7, 2022

• Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization

  GeroScience, Dec 22, 2021