Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

• NCT06325943

  Collaborator, Phase 3, Completed, 37 people, Mar 22, 2024

• NCT04845919

  Phase 2, Completed, 5 people, Apr 15, 2021

• NCT04224441

  Collaborator, Phase 2, Status unknown, 41 people, Jan 13, 2020

• Rapamycin Treatment for ALS

  Collaborator, Phase 2, Completed, 63 people, Dec 2, 2017

• NCT03345940

  Phase 4, Terminated, 55 people, Nov 17, 2017

• NCT00877604

  Phase 2, Completed, 34 people, Apr 8, 2009

Sources: clinicaltrials.gov

• European Commission

  HORIZON-RIA, Continuous stratification for improved prevention, treatment, and rehabilitation of stroke patients using digital twins and AI, 101080875, €251K, 2023–2027, Apr 21, 2023

Sources: cordis.europa.eu

• Peripheral microRNA signature in genetic frontotemporal dementia-findings from the GENFI initiative

  Apr 11, 2026

• Cerebrovascular Reactivity at Rest and Its Association With Cognitive Function in People With Genetic Frontotemporal Dementia

  Sep 4, 2025

• Social Network and Environment as Determinants of Disability and Quality of Life in Aging: Results From an Italian Study

  May 23, 2022

• A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

  Nov 27, 2021

• Predictors of COVID-19 outcome in Parkinson's disease

  Aug 13, 2020

• Theory of mind across lifespan from ages 16 to 81 years

  Jul 30, 2019

• Kruppel-like factor 4 regulates keratinocyte senescence

  RF-2016-02362541, Mar 26, 2018

• Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly: Effects of data-driven physiological noise correction techniques

  Mar 17, 2016

Sources: openalex.org, api.crossref.org

• Cerebrospinal fluid YWHAG:NPTX2 ratio predicts clinical severity and future phenoconversion in frontotemporal lobar degeneration

  bioRxiv, Aug 31, 2026

• Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging

  Nature aging, Jul 1, 2026

• The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence

  Nature neuroscience, Jun 27, 2026

• Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementias

  Nature genetics, Jun 4, 2026

• Peripheral microRNA signature in genetic frontotemporal dementia-findings from the GENFI initiative

  GeroScience, Apr 11, 2026

• Protecting the aging mind: how cognitive reserve and lifestyle factors relate to executive functions and long-term memory

  Aging clinical and experimental research, Mar 26, 2026

• The burden of disease in Italy, 1990-2023: a subnational analysis from the Global Burden of Disease Study 2023

  Epidemiologia e prevenzione, Mar 19, 2026

• Exploring cortical excitability modulation to promote cognitive resilience in aging: an rTMS study protocol

  Frontiers in human neuroscience, Mar 12, 2026

• Composite grey matter fingerprints for genetic frontotemporal dementia

  Journal of neurology, neurosurgery, and psychiatry, Feb 13, 2026

• Electroencephalography-based signatures of cognitive resilience in individuals with stable mild cognitive impairment despite carrying a high-risk for progression to dementia

  Alzheimer's & dementia (New York, N. Y.), Dec 22, 2025

• Detection of TDP-43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS

  Alzheimer's & dementia : the journal of the Alzheimer's Association, Dec 16, 2025

• Cellular signatures underlying functional resilience in presymptomatic frontotemporal dementia

  Brain : a journal of neurology, Nov 24, 2025

• Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging

  Nature aging, Sep 25, 2025

• Cerebrovascular Reactivity at Rest and Its Association With Cognitive Function in People With Genetic Frontotemporal Dementia

  Neurology, Sep 4, 2025

• The impact of slow mobility and built environment characteristics on 12.5-year all-cause mortality among older women and men: A prospective cohort study from Poland

  SSM - population health, Jul 23, 2025

• Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice

  International journal of molecular sciences, May 28, 2025

• Anatomical progression of genetic frontotemporal lobar degeneration across the lifespan

  Brain : a journal of neurology, May 27, 2025

• The SIRT1 activator SRT2104 exerts exercise mimetic effects and promotes Duchenne muscular dystrophy recovery

  Cell death & disease, Apr 7, 2025

• Cortico-Cortical Paired Associative Stimulation (ccPAS) in Ageing and Alzheimer's Disease: A Quali-Quantitative Approach to Potential Therapeutic Mechanisms and Applications

  Brain sciences, Mar 28, 2025

• It's Never Too Early, It's Never Too Late: The Potential of Health Behaviors for Cardiovascular Health in Nonagenarians. Data From the Mugello Study

  The journals of gerontology. Series A, Biological sciences and medical sciences, Mar 25, 2025