Alzheimer's Research Trust

• Zoe Kourtzi

  Lead investigator

Sources: openalex.org

• NCT07724132

  Collaborator, Phase 3, Recruiting, 1,200 people, Jul 23, 2026

• ASCEND: A Study of Cardiovascular Events iN Diabetes

  Collaborator, Phase 4, Active, not recruiting, 15,480 people, Aug 25, 2005

Sources: clinicaltrials.gov

• Alzheimer's Drug Discovery Foundation

  Diagnostics Accelerator, Integration of multiple digital technologies for the early detection of neurodegenerative diseases, ADDF-21317511, $1.2M, 2021–2024, Jun 1, 2021

Sources: openalex.org

• Alzheimer's disease risk gene Wwox controls amyloid pathology through metabolic reprogramming

  ARUK-PG2023B-003, Oct 9, 2026

• Evaluating Diabetes Drug Targets for Vascular Dementia Prevention Using Drug Target Mendelian Randomisation

  ARUK-SRF2023B-008, Sep 29, 2026

• Changes in Adrenergic and Cholinergic Receptors on Human Cerebral Vessels

  5345, Sep 25, 2026

• Clonal Haematopoiesis Tracks Alzheimer's-like Cortical Atrophy in Community-Dwelling Older Adults

  Sep 12, 2026

• Amyloid-PET pipeline choice influences classification of preclinical Alzheimers disease

  ARUK-PG2014-1946, ARUK-PG2017-1946, Aug 19, 2026

• Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities

  Aug 5, 2026

• Cellular signatures underlying functional resilience in presymptomatic frontotemporal dementia

  ARUK-RADF2021A-010, Aug 3, 2026

• Senescence Markers and Associated Transcriptomic Changes Are Expressed at Early Stages of Alzheimer's Neuropathology but Are Not Independently Related to Dementia

  ARUK PG2013A-003, Aug 3, 2026

• BOLD fMRI activations and LC contrast associated with successful episodic memory in healthy older adults and MCI

  SRF2018B‐004, Aug 1, 2026

• Hormone replacement therapy and dementia risk among postmenopausal women: Identifying responsive subgroups in the UK Biobank

  Aug 1, 2026

• Automated quantification of white matter hyperintensity confluence: A measure of spatial organisation beyond volume and visual rating scales

  ARUK-SRF2023B-005, Jul 28, 2026

• Persistent financial adversity and cognitive aging: a life course investigation

  ARUK-PG2014-1946, ARUK-PG2017-1946, Jul 23, 2026

• NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy model

  Jul 22, 2026

• Real-world deployment of remote sleep monitoring technologies reveals distinct patterns associated with cognitive decline

  Jul 21, 2026

• Multi-threshold polygenic risk improves hippocampal-based cognitive decline prediction

  Jul 17, 2026

• Structural MRI across lifespan reveals differential thalamic trajectories in Down syndrome

  ARUK-RF2021B-001, Jul 1, 2026

• Sexually dimorphic behavioural signatures of tau toxicity in adult Drosophila

  ARUK-RADF-2019a-001, ARUK-EG2016A-6, Jun 25, 2026

• Plasma proteomic signatures of cellular aging predict human disease

  ARUK-PG2017-1946, Jun 15, 2026

• Composite grey matter fingerprints for genetic frontotemporal dementia

  ARUK-CRF2017B-2, Jun 12, 2026

• Proteomic Signatures of Neuropathological Alterations in Alzheimer’s Disease: Insights from the Bio-Hermes Study

  ARUK-RF2020A-005, ARUK-SRF2023B-007, May 22, 2026

Sources: api.crossref.org, openalex.org, pubmed.ncbi.nlm.nih.gov

• Insulin resistance and brain health in midlife: a potential dementia prevention target

  Grants or research support, Aug 21, 2026

• Amyloid-PET pipeline choice influences classification of preclinical Alzheimers disease

  Board or leadership role, Aug 19, 2026

• Effect of semaglutide on kidney outcomes in the SELECT, FLOW, and SOUL trials: a prespecified pooled analysis

  Fees or honoraria, Grants or research support, Aug 7, 2026

• Plasma proteomic signatures of cellular aging predict human disease

  Board or leadership role, Jun 15, 2026

• Cellular Aging Signatures in the Plasma Proteome Record Human Health and Disease

  Board or leadership role, Feb 12, 2026

• Retention and longitudinal change in Insight 46, an intensive neuroscience sub-study of the 1946 British birth cohort

  Board or leadership role, Jan 22, 2026

• Ticking Differently: Elucidating Sexual Dimorphism in Human Aging through Metabolomics, Proteomics and Genomics

  Grants or research support, Oct 31, 2025

• Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study

  Grants or research support, Aug 22, 2024

Sources: pubmed.ncbi.nlm.nih.gov, europepmc.org

• Effect of thiazolidinediones compared to other antidiabetic medications on incident dementia in people with type 2 diabetes: A target trial emulation study

  medRxiv, Mar 20, 2026

• Childhood predictors of dementia and mortality: 78 year follow-up of the 1946 British Birth Cohort

  medRxiv, Mar 9, 2026

• Drug repurposing for Alzheimer's disease: a Delphi consensus and stakeholder consultation

  Alzheimer's research & therapy, Nov 18, 2025

• Brain age prediction and early neurodegeneration detection using contrastive learning on brain biomechanics: a retrospective, multicentre study

  EBioMedicine, Nov 2, 2025

• Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study

  The lancet. Healthy longevity, Sep 15, 2022

• Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study

  The lancet. Healthy longevity, Jun 1, 2022

• Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Aug 17, 2018