Alcon
CompanyUnited StatesFounded 1945
Alcon develops 6 assets, the furthest approved (ENCELTO in macular telangiectasia type 2). Mostly small molecule and cell therapy acting on CNTFR, PTGS2 and PTGS1; based in the United States, founded in 1945.
- 6
- Assets
- Furthest stage
- Approved
- 13
- Trials
- 6
- Signals
Pipeline
6Activates ocular TRPM8 receptors to stimulate tear production through sensory neural signaling.
Approved, Small molecule, dry eye syndrome (Phase 3)
Encapsulated engineered cells secrete ciliary neurotrophic factor to slow retinal photoreceptor loss.
Approved, Cell therapy, CNTFR, macular telangiectasia type 2
Nepafenac Ophthalmic Suspension, 0.3%
NSAID prodrug inhibiting cyclooxygenase 1 and 2 to reduce ocular inflammation.
Phase 3, Small molecule, PTGS2, PTGS1, cataract, non-proliferative diabetic retinopathy
3 more assets
Full company profiles: pipeline, trials, funding and people.
Subsidiaries
15 assets, 13 trials
In the full profile
- Evidence behind the mechanisms6
- Trials18
- Signals7
- Similar companies6
Papers
Japanese journal of ophthalmology, Jul 9, 2025
Accumulation of pTreg cells is detrimental in late-onset (aged) mouse model of multiple sclerosis
Aging cell, May 27, 2022
Accumulation of Treg cells is detrimental in late-onset (aged) mouse model of multiple sclerosis
bioRxiv (Cold Spring Harbor Laboratory), Dec 17, 2021