Vertebral fracture assessment

2 papers1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

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1 lab in 1 country

Funder: National Evidence-based Healthcare Collaborating Agency

Humans1

Associations

Vertebral fracture

upin humans1

1 study

Vertebral fracture assessment predicts vertebral fracture in humans (sensitivity 0.70-0.93, specificity 0.95-1.00 (per-vertebra); sensitivity 0.65-1.00, specificity 0.74-1.00 (per-patient)).
“VFA appeared to have moderate sensitivity and high specificity for detecting VFs when compared with spinal radiography.”
Reviewwhen compared with spinal radiography
A systematic review of diagnostic accuracy of vertebral fracture assessment (VFA) in postmenopausal women and elderly men
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA18 Jan 2016