Toxicogenetic ablation of cholinergic interneurons

Exposure

1 paper studies it1 finding

  • 1 lab in 1 country
  • Funders: Australian Research Council and 3 more
  • Animals1

Outcomes

1

Goal-directed learning

downin mice1

1 study
  1. Toxicogenetic ablation of cholinergic interneurons impair goal-directed learning in mice.

    “Toxicogenetic ablation of CINs in young mice reproduced these behavioral and neuronal defects”

    Animalstoxicogenetic ablation of cholinergic interneuronsstriatum

    Aging-Related Dysfunction of Striatal Cholinergic Interneurons Produces Conflict in Action Selection

    Neuron

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