Neuro-oncology
Drug combination limited brain tumor regrowth in mice
In mice carrying childhood brain tumor models, trametinib plus navitoclax reduced regrowth after treatment stopped and improved survival.In mice carrying childhood brain tumor models, trametinib plus navitoclax reduced regrowth after treatment stopped and improved survival.
Mouse studyInterventions
Who was studiedMice with transplanted BT-40 tumors
What changedTrametinib plus navitoclax reduced brain tumor regrowth in mice after treatment stopped
The catchSide effects of the drug combination were not reported