TLN-01
Intervention1 paper4 findings
- Human trial1
Outcomes
4Kynurenine
upin humans1Moderate certainty
1 study
Kynurenine
upin humans1Moderate certainty
TLN-01 increases kynurenine in humans.
Human trialsarcopenia8 weeksn = 34
Effects of a Multi-Ingredient MCT-Leucine-Creatine-Based Supplement (TLN-01) on Muscle Mass, Strength, and Plasma Amino Acid Profiles in Older Adults with Sarcopenia: A Randomized Controlled Trial · Life (Basel, Switzerland) · 14 Aug 2026
1-methylhistidine
downin humans1Moderate certainty
1 study
1-methylhistidine
downin humans1Moderate certainty
TLN-01 decreases 1-methylhistidine in humans.
Human trialsarcopenia8 weeksn = 34
Effects of a Multi-Ingredient MCT-Leucine-Creatine-Based Supplement (TLN-01) on Muscle Mass, Strength, and Plasma Amino Acid Profiles in Older Adults with Sarcopenia: A Randomized Controlled Trial · Life (Basel, Switzerland) · 14 Aug 2026
Handgrip strength
no changein humans1Moderate certainty
1 study
Handgrip strength
no changein humans1Moderate certainty
TLN-01 has no effect on handgrip strength in humans.
Human trialsarcopenia8 weeksn = 73
Effects of a Multi-Ingredient MCT-Leucine-Creatine-Based Supplement (TLN-01) on Muscle Mass, Strength, and Plasma Amino Acid Profiles in Older Adults with Sarcopenia: A Randomized Controlled Trial · Life (Basel, Switzerland) · 14 Aug 2026
Appendicular skeletal muscle mass
upin humans1Moderate certainty
1 study
Appendicular skeletal muscle mass
upin humans1Moderate certainty
TLN-01 increases appendicular skeletal muscle mass in humans (+0.42 kg, +3.2%).
Human trialsarcopenia8 weeksn = 34
Effects of a Multi-Ingredient MCT-Leucine-Creatine-Based Supplement (TLN-01) on Muscle Mass, Strength, and Plasma Amino Acid Profiles in Older Adults with Sarcopenia: A Randomized Controlled Trial · Life (Basel, Switzerland) · 14 Aug 2026