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Targeted high-density microperimetry testing

Targeted high-density microperimetry testing has been studied in 1 paper since 2023: 1 observational study in people. The newest paper, Oct 30, 2023: “Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration”.

Exposure

1 paper studies it2 findingsUpdated

See all 1

“magnitude of visual sensitivity abnormalities based on MS, PSD and the number of deep defects were all significantly greater in eyes with nGA using targeted, high-density microperimetry testing compared with eyes with nGA using standard central microperimetry testing”
Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular DegenerationOphthalmology science2023doi:10.1016/j.xops.2023.100419

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Apellis Pharmaceuticals and 5 more
  • Humans1

What did studies of Targeted high-density microperimetry testing find?

2

Studies of Targeted high-density microperimetry testing measured 2 outcomes; the most studied are Measurement error (1 study) and detection of visual sensitivity abnormalities (1).

Measurement error

downin humans1

1 study

  1. Targeted high-density microperimetry testing decreases measurement error in humans (0.9 dB vs 1.8 dB).

    “intrasession coefficient of repeatability, where 95% of the test-retest differences are expected to occur, for MS in eyes with atrophic changes was 0.9 dB with the targeted, high-density microperimetry testing, and 1.8 dB with standard central microperimetry testing”

    Humanseyes with atrophic lesions

    Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration

    Ophthalmology science

Detection of visual sensitivity abnormalities

upin humans1

1 study

  1. Targeted high-density microperimetry testing increases detection of visual sensitivity abnormalities in humans (P < 0.001).

    “magnitude of visual sensitivity abnormalities based on MS, PSD and the number of deep defects were all significantly greater in eyes with nGA using targeted, high-density microperimetry testing compared with eyes with nGA using standard central microperimetry testing”

    Humanseyes with nascent geographic atrophy (nGA)

    Targeted High-Density Microperimetry Testing of Nascent Geographic Atrophy in Age-Related Macular Degeneration

    Ophthalmology science

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