Transcranial direct current stimulation + tai chi

Transcranial direct current stimulation + tai chi has been studied in 4 papers since 2023: 2 trials in people, 1 review; 2 in the past year. The newest paper, Apr 6, 2026: “Effects of non-invasive brain stimulation combined with Tai Chi on the physical, cognitive, emotional, sleep, and quality-of-life outcomes in older adults: A systematic review and meta-analysis”.

Intervention

4 papers study it5 findingsUpdated

See all 4 papers on transcranial direct current stimulation + tai chi

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“The Tai Chi combined with tDCS group demonstrated a significantly greater reduction in WOMAC Pain subscores compared to the Health Education Control group (P < 0.001)”
Effects of Tai Chi combined with transcranial direct current stimulation on pain in knee osteoarthritis: a randomized controlled neuroimaging trialBMC medicine2026doi:10.1186/s12916-026-04760-9

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Funders: Fujian University of Traditional Chinese Medicine and 3 more
  • Human trial2

Studies in people

2 studies gave transcranial direct current stimulation + tai chi to people and measured what changed.

What changedDesignPeopleSource

down: Decreases painmean difference, − 6.42 [95% CI, − 8.65 to − 4.19]

down: Decreases resting-state functional connectivity

Randomized trial12-week152 peopleaged 50 to 80 yearsIndividuals with KOABMC medicine, Mar 17, 2026

up: Improves cognitive function

up: Improves memory function

Randomized trial12 weeks180 peopleBothaged between 50 and 75 yearsParticipants with MCI from the communityFrontiers in public health, Aug 7, 2023

What did studies of transcranial direct current stimulation + tai chi find?

4

Studies of transcranial direct current stimulation + tai chi measured 4 outcomes; the most studied are pain (1 study), resting-state functional connectivity (1) and memory function (1).

Pain

downin humans1

1 study
  1. Transcranial direct current stimulation + tai chi decreases pain in humans (mean difference, − 6.42 [95% CI, − 8.65 to − 4.19]).

    “WOMAC Pain subscores were significantly lower in the Tai Chi combined with tDCS group (mean difference, − 6.42 [95% CI, − 8.65 to − 4.19]; P < 0.001”

    Human trial12-weekn = 152

    Effects of Tai Chi combined with transcranial direct current stimulation on pain in knee osteoarthritis: a randomized controlled neuroimaging trial

    BMC medicine

  2. Transcranial direct current stimulation + tai chi decreases pain in humans (knee osteoarthritis) (P < 0.001).

    “The Tai Chi combined with tDCS group demonstrated a significantly greater reduction in WOMAC Pain subscores compared to the Health Education Control group (P < 0.001)”

    Human trialknee osteoarthritis12-weekn = 152

    Effects of Tai Chi combined with transcranial direct current stimulation on pain in knee osteoarthritis: a randomized controlled neuroimaging trial

    BMC medicine

Resting-state functional connectivity

downin humans1

1 study
  1. Transcranial direct current stimulation + tai chi decreases resting-state functional connectivity in humans.

    “when compared to Health Education Control group, Tai Chi combined with tDCS group, Tai Chi group and tDCS group significantly decreased rsFC on DLPFC_R-PCC_L, DLPFC_R-Thalamus_L, DLPFC_R-Thalamus_R, DLPFC_R-Precunues_L, and DLPFC_R-SFG_L, respectively”

    Human trial12-weekn = 121

    Effects of Tai Chi combined with transcranial direct current stimulation on pain in knee osteoarthritis: a randomized controlled neuroimaging trial

    BMC medicine

More on Resting-state functional connectivity

Memory function

upin humans1

1 study
  1. Transcranial direct current stimulation + tai chi improves memory function in humans.

    “The results showed a statistically significant difference among the four groups (P = 0.015, F (3,173) = 3.584), and post-hoc analysis showed that TCT was more effective than TCS, WAT, and WAS (P = 0.022, P = 0.024, and P = 0.002, respectively).”

    Human trial12 weeksn = 180

    Effects of Tai Chi combined with tDCS on cognitive function in patients with MCI: a randomized controlled trial

    Frontiers in public health

Cognitive function

upin humans1

1 study
  1. Transcranial direct current stimulation + tai chi improves cognitive function in humans.

    “post-hoc analysis showed that TCT was more effective compared with TCS, WAT, and WAS (P = 0.012, P = 0.032 and P < 0.001, respectively”

    Human trial12 weeksn = 180

    Effects of Tai Chi combined with tDCS on cognitive function in patients with MCI: a randomized controlled trial

    Frontiers in public health

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 02 papers in 12 months